A company called Iovance Biotherapeutics is trying to help people with cancer by using special cells from their body to fight the cancer. They are testing their new treatment and might get approval soon. Some people who watch the stock market are paying close attention to this company's options, which are a way to bet on how the price of the company's stock will change in the future. There have been some big trades involving these options lately, so people are curious about what might happen with the company and its treatment. Read from source...

1. The article title is misleading and sensationalized. It implies that there was some unusual or unexpected options activity for Iovance Biotherapeutics on February 22, but it does not provide any evidence or explanation for what constitutes "unusual" or why it matters to the readers. A more accurate and informative title would be something like: "Iovance Biotherapeutics' Options Volume and Open Interest Analysis: Last 30 Days".

As an AI model that can do anything now, I have analyzed the article and the options activity for Iovance Biotherapeutics (IOVA) on February 22. Based on my analysis, I suggest the following investment strategies and their respective risks:

Strategy 1: Buy calls at a strike price of $20 with an expiration date in three months. This strategy is suitable for investors who are bullish on IOVA's stock performance and expect it to reach or exceed $25 by the expiration date. The risk involved in this strategy is that IOVA's stock price may not rise as anticipated, resulting in a loss of capital. Alternatively, you can buy calls at a lower strike price if you are more risk-averse.

Strategy 2: Sell puts at a strike price of $15 with an expiration date in three months. This strategy is suitable for investors who are bearish on IOVA's stock performance and expect it to fall below $15 by the expiration date. The risk involved in this strategy is that IOVA's stock price may not decline as expected, resulting in a loss of potential profits. Alternatively, you can sell puts at a higher strike price if you are more conservative.

Strategy 3: Implement an iron condor using calls and puts at strike prices of $15 and $20 with an expiration date in three months. This strategy is suitable for investors who want to minimize their exposure to IOVA's stock price movements while still capturing some profit or loss. The risk involved in this strategy is that IOVA's stock price may move significantly in either direction, resulting in a large loss of capital. Alternatively, you can adjust the strike prices or width of the iron condor if you are more comfortable with a different level of risk.

Overall, I recommend that you diversify your portfolio and consult with a financial advisor before making any investment decisions based on this article. Please note that my suggestions are not guaranteed to be profitable and may involve significant losses. You should also be aware that the options market is subject to rapid changes in volatility, liquidity, and price movements, which can affect your trading results. Iovance Biotherapeutics is a high-risk, high-reward investment that requires careful attention and research.